Talk:Alpha-fetoprotein

Medicine Mid‑importance

	Medicine portal This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine articles
Mid	This article has been rated as Mid-importance on the project's importance scale.

Molecular Biology: MCB

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles
???	This article has not yet received a rating on the importance scale.
	This article is supported by the Molecular and Cell Biology task force (assessed as Mid-importance).

Women's Health Mid‑importance

	This article is within the scope of WikiProject Women's Health, a collaborative effort to improve the coverage of Women's Health on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Women's HealthWikipedia:WikiProject Women's HealthTemplate:WikiProject Women's Healthwomen's health articles
Mid	This article has been rated as Mid-importance on the importance scale.

NEW

Abnormal AFP values

The AFP value of 500ng/ml seems very high, according to http://emedicine.medscape.com/article/454477-workup#a0719 a level of > 9 ng/ml is considered abnormal in context of testicular cancer? — Preceding unsigned comment added by 82.161.33.118 (talk) 22:11, 20 March 2013 (UTC)[reply]

RECAF

RECAF, cell membrane receptor for AFP, may be useful as a tumor marker itself: http://www.devicelink.com/ivdt/archive/05/06/004.html and newer: https://www.novapublishers.com/catalog/product_info.php?products_id=58825

Need to look into this. Una Smith 04:11, 12 June 2007 (UTC)[reply]

The AFP receptor (AFPR) is an oncofetal antigen which unlike AFP is re-expressed by most types of cancer: https://www.novapublishers.com/catalog/product_info.php?products_id=58825. AFPR is not a universal tumor marker: https://www.ncbi.nlm.nih.gov/pubmed/29211355. In addition to embryotic and cancer cells AFPR is expressed by myeloid-derived suppressor cells (MDSCs): https://www.ncbi.nlm.nih.gov/pubmed/28956104. MDSC can be targeted through AFPR: https://doi.org/10.4155/fsoa-2018-0029 and be used for the treatment of autoimmune diseases and cancer: https://www.ncbi.nlm.nih.gov/pubmed/29216804 https://doi.org/10.4155/tde-2018-0068. — Preceding unsigned comment added by Aimpila (talk • contribs) 18:16, 8 January 2019 (UTC)[reply]

AFPep treats breast cancer

Sciencenews magazine, vol 168, p307, 11/12/05, reports that James Bennett of the Albany (N.Y.) Medical College and colleagues have synthisized a ring-shape peptide called AFPep. This checks the progress of breast cancers in mice as well as Tamoxifen, and when given with Tamoxifen an even greater effect is observed.

Is this a major trend in research? Are there other studies duplicating this result? When are phase I trials expected? At this juncture I'm not sure if this should be included in this article just yet. JFW | T@lk 19:56, 24 November 2005 (UTC)[reply]

I presume we're talking about DeFreest LA, Mesfin FB, Joseph L, McLeod DJ, Stallmer A, Reddy S, Balulad SS, Jacobson HI, Andersen TT, Bennett JA. Synthetic peptide derived from alpha-fetoprotein inhibits growth of human breast cancer: investigation of the pharmacophore and synthesis optimization. J Pept Res 2004;63:409-19. PMID 15140158. JFW | T@lk 19:58, 24 November 2005 (UTC)[reply]

OLD

merge

Possible merge with AFP screening?

Yep, that's what i did. The part copied from there may be referring more to the triple test, than to afp alone. I have to establish this before i change it too much. Tristanb 01:04, 5 August 2005 (UTC)[reply]

Wikipedia:Interlanguage links

The link to the Chinese page seems to be a dead-end. Una Smith 17:16, 9 April 2007 (UTC)[reply]

You'll need an account with zh.wikipedia to create the new page. My en.wikipedia account cannot access it too. Since you might have problem with Chinese, do you want me help you create an account there? Samantha 02:40, 10 April 2007 (UTC)[reply]