Talk:Chagas disease

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May 20, 2010	WikiProject peer review	Reviewed
May 9, 2020	Featured article review	Kept

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Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Chagas disease.

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The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

Copyvio check

Regarding this impressive edit by José Eymard H. Pittella, I am concerned if the paraphrasing is too close. SandyGeorgia (Talk) 21:59, 4 April 2020 (UTC)[reply]

For now, I have commented out the text but left it in the article;[1] if others feel there is no other way to paraphrase the text in our words, they can uncomment it, but it also needs some attention to wikilinking, jargon, etc. SandyGeorgia (Talk) 22:02, 4 April 2020 (UTC)[reply]

Source:

Many patients present a pseudotumoral form (cerebral chagoma), characterized by the presence of single or multiple necrotic-hemorrhagic nodular lesions, usually located in the white matter of the cerebral lobes and, less frequently, in the brainstem and cerebellum

Text:

Many patients have the pseudotumoral form (brain ‘chagoma’), characterized by the presence of single or multiple necrotic-hemorrhagic nodular lesions, usually located in the white matter of the cerebral lobes and, in some cases, in the brain stem and cerebellum.

Source:

The classic manifestations are those of acute meningoencephalitis, with fever, headache, meningism, convulsions, altered mental state, vomiting, and focal neurological deficits.

Text:

The clinical manifestations of CNS involvement in reactivated Chagas disease are characterized by fever, headache, vomiting, seizures, and focal neurological signs.

Source:

Since the 1980s, with the beginning of the use of immunosuppressants and of organ transplants, as well as with the emergence of HIV, clinical conditions appeared for the reactivation of the pre-existing chronic infection caused by T. cruzi, with severe repercussions, especially in the CNS.

Text:

The use of corticosteroids, immunosuppressors and cytostatic agents, the progress in organ transplantation, and in particular the emergence of AIDS in 1981 have set conditions for infection reactivation in chronic chagasic patients.

Yes, I believe they're new here and the author of the textbook chapter, so I assume the very close paraphrasing is inadvertent (though still a problem of course). I've left a message at their talk page. I'll get a chance to work on this article again in the next few days, and will try to add some info on HIV+ Chagas reactivation (if someone doesn't beat me to it). Thanks for checking that. Sorry for the slow pace here! Ajpolino (talk) 22:31, 4 April 2020 (UTC)[reply]

Slow and steady wins the race! SandyGeorgia (Talk) 22:33, 4 April 2020 (UTC)[reply]

When you all get to this, please remember that this text is still in the article, but hidden by commenting it out with inline comments. SandyGeorgia (Talk) 10:53, 9 April 2020 (UTC)[reply]

Text

Linked triatomine bug and changed to singular rather than plural. Also added the common name "kissing bug" in brackets as that will be far more recognizable.

Change fetus to baby as can happen during the birth process and the resulting child is what is infected. Doc James (talk · contribs · email) 20:42, 19 April 2020 (UTC)[reply]

I'm not sure whether my thoughts are in the right place here! Instead of '… %-age of people …' I would rather choose '… of cases or infected people …'. Thanks for letting me share. Lodidol (talk) 12:24, 28 November 2020 (UTC)[reply]

Hi Lodidol, your thoughts are welcome here. Pardon my thickness, but could you please quote the text you'd like changed? I'm not sure I understand your suggestion. Thanks! Ajpolino (talk) 19:36, 28 November 2020 (UTC)[reply]

@Ajpolino Sorry for my late reply! (I think I could use quite some help to cope with technical issues pertaining Wikipedia in general!) I just screened the article on Chagas for '%' and could not find anything ambiguous in the wording! Maybe I was wrong altogether with my original suggestion! Please forgive me. Lodidol (talk) 14:30, 27 October 2021 (UTC)[reply]

Vaccine

Hey, Spicy; the lead says no vaccine as of 2019. Can PMID 34141721 be used to update this to 2021? SandyGeorgia (Talk) 18:07, 24 March 2022 (UTC)[reply]

I guess it's not an exceptional claim, but that's a dodgy journal. I added a better (and more recent) source. Spicy (talk) 22:54, 24 March 2022 (UTC)[reply]

Excellent; thanks, and good luck! SandyGeorgia (Talk) 23:35, 24 March 2022 (UTC)[reply]

Transmission

Please see https://www.who.int/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis) as it cites transmission through frass, and the smearing of it in open wounds, rather than the act of piercing the skin with mouth-parts itself. ZoologyRules (talk) 04:03, 18 November 2022 (UTC)[reply]

... That's what our article says too... T. cruzi replicates in the insect's intestinal tract and is shed in the bug's feces. When an infected triatomine feeds, it pierces the skin and takes in a blood meal, defecating at the same time to make room for the new meal. The bite is typically painless, but causes itching. Scratching at the bite introduces the T. cruzi-laden feces into the bite wound, initiating infection. Ajpolino (talk) 05:20, 18 November 2022 (UTC)[reply]